GENOMIC ANALYSIS OF THE SUMO-CONJUGATING ENZYME AND GENES UNDER ABIOTIC STRESS IN POTATO (SOLANUM TUBEROSUM L.)

Genomic Analysis of the SUMO-Conjugating Enzyme and Genes under Abiotic Stress in Potato (Solanum tuberosum L.)

SUMO-conjugating enzymes (SCE) and SUMO (Small Ubiquitin-Like Modifiers) genes are important components of SUMOylation.SCE has a crucial role during the SUMOylation process which acts as a catalyst to transfer SUMO to the target protein.Comprehensive studies on SCE and SUMO have been performed in some plants, but studies on these genes remain limit

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Environmental changes during marl-limestone formation: evidence from the Gargasian (Middle Aptian) of La Marcouline Quarry (Cassis, SE France)

Limestone-marl alternations are usually interpreted to reflect cyclic paleoenvironmental fluctuations linked to Milankovitch-scale climate variations.However, the impact of diagenesis on lithological differentiation can be overprinted on the primary signal.In order to evaluate environmental variations during the deposition of the Gargasian hemipela

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Advances in the regulatory mechanisms of mTOR in necroptosis

The mammalian target of rapamycin (mTOR), an evolutionarily highly conserved serine/threonine protein kinase, plays a prominent role in controlling gene expression, metabolism, and cell death.Programmed cell Side Rails death (PCD) is indispensable for maintaining homeostasis by removing senescent, defective, or malignant cells.Necroptosis, a type o

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MICROVASCULAR CHANGES AND DIABETIC RETINOPATHY AND NEPHROPATHY PROGRESSION IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS

Background: We established that the age at inception of T1DM significantly impacts the long-term risk of developing proliferative retinopathy in affected children and adolescents.Patients with T1DM, diagnosed before the age of 15 are at a significantly higher risk than children diagnosed at age 15 and older.For instance, several studies show change

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